Hughes' Syndrome
Microscopic photograph of a blood clot.
In 1983, our group described a condition in which there was an increased tendency to blood clotting. Such clots can occur at any time, and can affect veins or arteries anywhere in the body.
During pregnancy, clotting of the placenta results in a tendency to miscarriage - some women suffering a dozen or more miscarriages before correct diagnosis and treatment.
Features include leg and arm clots (DVTs), headache and migraine (leading in some to stroke), memory loss, chest pain, cold circulation. We initially reported the condition in a group of lupus patients but soon recognised that it could occur in individuals without any evidence of lupus.
The first description of Hughes' Syndrome (one of a number of publications in 1983).
